Cancer Terms

Fosfomycin Tromethamine

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Anti-Infective Agent -> Urinary Anti-Infective Agent -> Fosfomycin Tromethamine

Fosfomycin Tromethamine Definition

The tromethamine salt form of fosfomycin, a synthetic broad-spectrum antibiotic. Fosfomycin tromethamine binds to and inactivates the enzyme enolpyruvyl transferase. This leads to an irreversible blockage of the condensation of uridine diphosphate-N-acetylglucosamine with p-enolpyruvate, which is one of the first steps of bacterial cell wall synthesis, thereby eventually causing cell lysis. In addition, fosfomycin tromethamine reduces the adherence of bacteria to uroepithelial cells. (NCI05)

Fosfomycin Tromethamine Synonyms

Fosfomycin Tromethamine, (1R,2S)-(1,2-Epoxypropyl)phosphonic Acid, compound with 2-Amino-2-(hydroxymethyl)-1,3-propanediol(1:1), FOSFOMYCIN TROMETHAMINE, Fosfomycin Trometamol Salt, Fosfomycin compound with Trometamol, Monurol

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