Gamma-Glutamylcysteine Synthetase Inhibitor

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Enzyme Inhibitor -> Gamma-Glutamylcysteine Synthetase Inhibitor

Gamma-Glutamylcysteine Synthetase Inhibitor Definition

Substances that inhibit gamma-Glutamylcysteine Synthetase, a rate-limiting enzyme in glutathione (GSH) biosynthesis, causing possible sensitization of tumor cells to alkylating agents, redox agents, and radiotherapy.

Gamma-Glutamylcysteine Synthetase Inhibitor Synonyms

Gamma-Glutamylcysteine Synthetase Inhibitor, GCS Inhibitors, Glutathione Synthesis Inhibitors

Terms in Gamma-Glutamylcysteine Synthetase Inhibitor category

Buthionine Sulfoximine