Ganciclovir Sodium
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Ganciclovir Sodium Definition
The sodium salt form of ganciclovir, a synthetic, antiviral, purine nucleoside analog with antiviral activity, especially against cytomegalovirus (CMV). Ganciclovir sodium is a prodrug that is phosphorylated and subsequently converted into its triphosphate form, the active metabolite ganciclovir-5-triphosphate (ganciclovir-TP), in the infected cells by cellular kinases. Ganciclovir-TP competes as a substrate with nucleotide triphosphates for viral DNA polymerase. Once it gets incorporated into DNA strand, it prevents further polymerization of DNA, thereby interfering with viral DNA replication.
Ganciclovir Sodium Synonyms
Ganciclovir Sodium, BIOLF-62, BW-759, BW-759U, Cymevene, Cytovene, DHPG Sodium, DHPG sodium, Denosine, GANCICLOVIR SODIUM, GCV Sodium, GCV sodium, Ganciclovir sodium, RS-21592
Terms in Ganciclovir Sodium category
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