General Transcription Factor 3B 90-kD Subunit
Cancer Terms ->
Retired Concepts ->
Retired Concept 2004 -> General Transcription Factor 3B 90-kD Subunit
General Transcription Factor 3B 90-kD Subunit Definition
Encoded by human BRF1 Gene (TFIIB Family), alternative isoforms 1 (677-aa, 74-kD), 2 (134-aa, altered N- and C-termini), 3 (473-aa, shorter N-terminus), and 4 (242-aa) of General Transcription Factor 3B 90-kD Subunit function at different promoters on tRNA, 5S rRNA, and other small RNA genes. Related to GTF2B (N-terminus), GTF3B contains a highly charged region and HMG2-related region. Essential for transcription initiation, GTF3B (C-terminus) binds TBP (collectively, TFIIIB) as one of three RNA polymerase III transcription factor subunits. Following GTF3A or GTF3C recognition of promoter elements, GTF3B and RNA polymerase III bind sequentially. (NCI)
General Transcription Factor 3B 90-kD Subunit Synonyms
General Transcription Factor 3B 90-kD Subunit, B-Related Factor 1, BRF, BRF1, BRF1 Homolog, BRF1 Homolog Subunit of RNA Polymerase III Transcription Initiation Factor IIIB, GTF3B, GTF3B 90-kD Subunit, General Transcription Factor IIIB 90kD Subunit, TAF3B2, TAF3C, TAFIII90, TATA Box Binding Protein (TBP)-Associated Factor 3C, TATA Box Binding Protein (TBP)-Associated Factor RNA Polymerase III Subunit 2, TATA Box-Binding Protein-Associated Factor RNA Polymerase III Subunit 2, TBP-Associated Factor RNA Polymerase III 90kD, TF3B90, TFIIIB90, Transcription Factor IIIB 90-kD Subunit, Transcription Initiation Factor IIIB, hBRF
Terms in General Transcription Factor 3B 90-kD Subunit category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.