Gentian Violet

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Gentian Violet Definition

A blue dye, extracted from plant of genus Gentiana, used in topical solution with antifungal and antimitotic properties. Gentian violet (GV) dissociates into positive (GV+) and negative ions (Cl-) that penetrate both gram-positive and gram-negative bacterial cells. The GV+ interacts with negatively charged components of the bacterial cell wall including lipopolysaccharides, peptidoglycan and DNA. This agent is a mutagen and mitotic poison, thereby inhibits cell growth. GV elicits a photodynamic action mediated by a free-radical mechanism. Furthermore, this agent dissipates action potential on the bacterial mitochondrial membrane by inducing permeability, thereby leading to respiratory inhibition and subsequent cell death.

Gentian Violet Synonyms

Gentian Violet, Basic Violet 3, CI 42555, Crystal Violet, GENTIAN VIOLET, Genapax, Hexamethyl-P-Rosaniline Chloride

Terms in Gentian Violet category

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