Cancer Terms

Granisetron Transdermal Patch

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Agent Affecting Nervous System -> Serotonin Antagonist -> Granisetron Transdermal Patch

Granisetron Transdermal Patch Definition

A transdermal system containing granisetron, a selective serotonin (5-HT) receptor antagonist, with antiemetic activity. Upon application of the transdermal patch to the skin and subsequent release into the bloodstream, granisetron selectively binds to and blocks the 5-HT subtype 3 (5-HT3) receptors located in the vagus nerve terminal and in the vomiting center in the central nervous system (CNS). By preventing stimulation of 5-HT3 receptors in the gastrointestinal (GI) tract, this agent is able to suppress chemotherapy-induced nausea and vomiting.

Granisetron Transdermal Patch Synonyms

Granisetron Transdermal Patch, 1-Methyl-N-(9-methyl-endo-9-azabicyclo(3.3.1)non-3-yl)-1H-indazole-3-carboxamide, Sancuso

Terms in Granisetron Transdermal Patch category



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