Cancer Terms

Growth Factor Oncogene

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Growth Factor Oncogene Definition

Mutated forms of growth factor genes which encode a diverse group of extracellular regulatory growth factor signaling molecules. These protein products play roles in the division, growth, proliferation, survival and differentiation of cells. Under normal cellular conditions, the activity of these proteins is tightly controlled. Activation of growth factor proto-oncogenes via mutation results in growth factor oncogenes. These aberrant genes express protein products that disrupt normal cell function.

Growth Factor Oncogene Synonyms

Oncogenes, Growth Factor

Terms in Growth Factor Oncogene category

Oncogene EGF
Oncogene HST
Oncogene MET
Oncogene SIS



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