Guanine Nucleotide-Releasing Factor-2
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Guanine Nucleotide-Releasing Factor-2 Definition
Ubiquitously expressed by human GRF2 Gene (as at least 2 alternative isoforms), Guanine Nucleotide-Releasing Factor-2 is an adaptor-type Ras-GEF/SH2-domain protein involved in signal transmission from cell surface to the nucleus. GRF2 binds to CRK and GRB2/ASH SH3 domains and transduces signals to activate RAS. (from LocusLink)
Guanine Nucleotide-Releasing Factor-2 Synonyms
Rap Guanine Nucleotide Exchange Factor 1, C3G Protein, CRK SH3-binding GNRP, GRF2, Guanine Nucleotide-Releasing Factor 2, Rap Guanine Nucleotide Exchange Factor (GEF) 1
Terms in Guanine Nucleotide-Releasing Factor-2 category
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