Gusperimus
Cancer Terms ->
Drugs and Chemicals ->
Pharmacologic Substance ->
Biological Response Modifier ->
Immunosuppressant -> Gusperimus
Gusperimus Definition
A derivative of the antitumor antibiotic spergualin with immunosuppressant activity. Gusperimus inhibits the interleukin-2-stimulated maturation of T cells to the S and G2/M phases and the polarization of the T cells into IFN-gamma-secreting Th1 effector T cells, resulting in the inhibition of growth of activated naive CD4 T cells; this agent may suppress growth of certain T-cell leukemia cell lines. (NCI04)
Gusperimus Synonyms
Gusperimus, (+-)-15-Deoxyspergualin, 1-Amino-19-guanidino-11-hydroxy-4,9,12-triazanonadecane-10,13-dione, 15-Deoxyspergualin, 15-Deoxyspergualin Hydrochloride, 7-{(Aminoiminomethyl)amino]-N-[2-[[4-[(3-aminopropyl)amino]butyl]amnio]-1-hydroxy-2-oxoethyl]heptanamide, BMS-181173, BMY-42215-1, DSG, Deoxyspergualin, Deoxyspergualin Hydrochloride, Gusperimus Trihydrochloride, N-[[[4-[(3-Aminopropyl)amino]-butyl]carbamoyl]hydroxymethyl]-7-guanidinoheptanamide, NKT-01, Spanidin
Terms in Gusperimus category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.