HOX11 wt Allele

Cancer Terms -> Gene -> Transcription Factor Gene -> Homeobox Gene -> HOX11 Gene -> HOX11 wt Allele

HOX11 wt Allele Definition

Human TLX1 wild-type allele is located in the vicinity of 10q24 and is approximately 7 kb in length. This allele, which encodes T-cell leukemia homeobox protein 1, plays roles in the regulation of RNA polymerase II-mediated transcription and in the development of the spleen. T-cell acute lymphoblastic leukemia is linked to both t(10,14)(q24;q11) and t(7,10)(q35;q24) translocations, resulting in fusion of this gene to either the T-cell receptor delta or beta locus.

HOX11 wt Allele Synonyms

TLX1 wt Allele, HOX11, Homeobox 11 Gene, T-Cell Leukemia, Homeobox 1 wt Allele, T-Cell Lymphoma 3-Associated Breakpoint Gene, TCL3, TCL3 Gene, TLX1

HOX11 wt Allele

HOX11 wt Allele Definition

HOX11 wt Allele Synonyms

Terms in HOX11 wt Allele category