Heat Shock Protein Inhibitor

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Heat Shock Protein Inhibitor

Heat Shock Protein Inhibitor Definition

Any agent that inhibits functions of heat shock proteins (Hsp). Hsps are a group of homodimeric molecular chaperones that interact with a diverse group of proteins, assisting in their folding and in the elimination of any misfolded or damaged molecules. Although transiently expressed during cell cycle in normal cells, Hsps are constitutively elevated in various types of cancer which raises the apoptosis threshold of these tumor cells and provides protection against cytotoxic agents. Hsp inhibitors may destabilize, and facilitate degradation of proto-oncoproteins leading to reversal of apoptosis regulation and cell death.

Heat Shock Protein Inhibitor Synonyms

Heat Shock Protein Inhibitor, Hsp Inhibitor

Heat Shock Protein Inhibitor

Heat Shock Protein Inhibitor Definition

Heat Shock Protein Inhibitor Synonyms

Terms in Heat Shock Protein Inhibitor category