Cancer Terms

Heterotrimeric G Protein Subunit Gene

Cancer Terms -> Gene -> Signaling Pathway Gene -> Heterotrimeric G Protein Subunit Gene

Heterotrimeric G Protein Subunit Gene Definition

Heterotrimeric G Protein Subunit Genes encode Heterotrimeric G Protein signal transducers, attached to the plasma membrane, that connect seven transmembrane cell surface G-protein coupled receptors to intracellular signal transduction effectors and pathways. Inactive G proteins consist of alpha/beta/gamma complexes that signal as dissociated GTP-bound alpha subunit or the beta/gamma complex. GTP hydrolysis by the inherent GTPase reverts the alpha subunit to its inactive (heterotrimeric) form. Receptors coupled to G proteins communicate signals from hormones, neurotransmitters, chemokines, and autocrine and paracrine factors. (NCI)

Heterotrimeric G Protein Subunit Gene Synonyms

Heterotrimeric G Protein Subunit Gene

Terms in Heterotrimeric G Protein Subunit Gene category

GNA12 Gene
GNAI1 Gene
GNAI2 Gene
GNAI3 Gene
GNAQ Gene
GNAS Gene
GNAZ Gene
GNB1 Gene
GNB2 Gene
GNB3 Gene



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