Cancer Terms

IL12RB2 wt Allele

Cancer Terms -> Gene -> Protein Complex Subunit Gene -> IL12RB2 Gene -> IL12RB2 wt Allele

IL12RB2 wt Allele Definition

Human IL12RB2 wild-type allele is located within 1p31.3-p31.2 and is approximately 90 kb in length. This allele, which encodes interleukin-12 receptor beta-2 chain protein, plays a role in the proliferation of both T cells and natural killer cells. It is also involved in Th1 cell differentiation. Up-regulation of the IL12RB2 gene is associated with certain infectious diseases such as Crohn's disease and leprosy.

IL12RB2 wt Allele Synonyms

IL12RB2 wt Allele, Interleukin 12 Receptor, Beta 2 wt Allele

Terms in IL12RB2 wt Allele category



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