INS316

Cancer Terms -> Drugs and Chemicals -> Industrial Aid -> Reagent -> Diagnostic Reagent -> INS316

INS316 Definition

A short-acting, aerosolized uridine 5-triphosphate (UTP) solution used as a diagnostic aid for lung cancer. INS316 appears to improve sputum expectoration mediated through the P2Y2 receptor, a nucleotide receptor expressed in human airway epithelial cells and some other tissues. UTP binding to the P2Y2 receptor triggers signal transduction that leads to chloride ion secretion, thereby resulting in mucociliary clearance of airway.

INS316 Synonyms

INS316, UTP Solution, Uridine 5-Triphosphate Solution

Terms in INS316 category

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