Inhibin Alpha

Cancer Terms -> Gene Product -> Protein -> Protein Complex Subunit -> Inhibin Alpha

Inhibin Alpha Definition

The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. (LocusLink)

Inhibin Alpha Synonyms

Inhibin Alpha, Alpha Inhibin, INHA

Inhibin Alpha

Inhibin Alpha Definition

Inhibin Alpha Synonyms

Terms in Inhibin Alpha category