Integrin-Linked Kinase
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Integrin-Linked Kinase Definition
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK encodes a predicted 451-amino acid protein, with an apparent molecular weight of 59 kD. The ILK protein is a serine/threonine protein kinase with 4 ankyrin-like repeats. ILK regulates integrin-mediated signal transduction. (LocusLink)
Integrin-Linked Kinase Synonyms
Integrin-Linked Kinase, ILK
Terms in Integrin-Linked Kinase category
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