Integrin-aVBeta3
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Protein or Riboprotein Complex -> Integrin-aVBeta3
Integrin-aVBeta3 Definition
Involved in cell adhesion and signaling, human Integrin-aVBeta3 is composed of type I membrane protein chains Integrin Alpha 5 (disulfide-linked heavy and light chains) and Integrin Beta 3 that recognize RGD sequences. Multiple heterodimeric alpha/beta combinations result in different integrins. aV/beta-3 is a receptor for cytotactin, fibronectin, laminin, MMP-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin, and von Willebrand factor. (NCI)
Integrin-aVBeta3 Synonyms
Integrin aVBeta3, Integrin Alpha-V/Beta-3, aVBeta3, aVBeta3 Integrin
Terms in Integrin-aVBeta3 category
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