Iodine I 123 Iodometomidate
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Iodine I 123 Iodometomidate Definition
An iodine I-123 conjugate of metomidate (MTO) with potential application in adrenal imaging. Metomidate is a potent and selective inhibitor of the cytochrome P-450 enzymes, especially CYP11B1 (11 beta-hydroxylase) and CYP11B2 (aldosterone synthase). Because both CYP11B1 and CYP11B2 are expressed exclusively in the adrenal cortex, I-123 iodometomidate can be used as a radiotracer for adrenal scintigraphy.
Iodine I 123 Iodometomidate Synonyms
Iodine I 123 Iodometomidate, I-123-IMTO
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