Cancer Terms

LAF4 wt Allele

Cancer Terms -> Gene -> Transcription Factor Gene -> LAF4 Gene -> LAF4 wt Allele

LAF4 wt Allele Definition

Human AFF3 wild-type allele is located within 2q11.2-q12 and is approximately 595 kb in length. This allele, which encodes AF4/FRM2 family member 3 protein, may play roles in both the activation of RNA polymerase II-directed transcription and the development of lymphoid tissues. Acute lymphoblastic leukemia is associated with rearrangement and fusion of this gene to the MLL gene.

LAF4 wt Allele Synonyms

AFF3 wt Allele, AF4/FMR2 Family, Member 3 wt Allele, LAF4, LAF4 Gene, Lymphoid Nuclear Protein Related to AF4 Gene

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