Cancer Terms

LIG4 wt Allele

Cancer Terms -> Gene -> DNA Repair Gene -> LIG4 Gene -> LIG4 wt Allele

LIG4 wt Allele Definition

Human LIG4 wild-type allele is located within 13q33-q34 and is approximately 11 kb in length. This allele, which encodes DNA ligase 4 protein, is involved in nonhomologous DNA end joining and in V(D)J recombination. Defects in the gene produce allelic variants that are the cause of LIG4 syndrome.

LIG4 wt Allele Synonyms

LIG4 wt Allele, DNA Ligase IV Gene, Ligase IV, DNA, ATP-Dependent wt Allele

Terms in LIG4 wt Allele category



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