Lidocaine Hydrochloride
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Lidocaine Hydrochloride Definition
The hydrochloride salt from of lidocaine, an aminoethylamide and a prototypical member of the amide class anesthetics. Lidocaine interacts with voltage-gated Na+ channels in the nerve cell membrane and blocks the transient increase in permeability of excitable membranes to Na+. This prevents the generation and conduction of nerve impulses and produces a reversible loss of sensation. Lidocaine hydrochloride also exhibits class IB antiarrhythmic effects. The agent decreases the flow of sodium ions into myocardial tissue, especially on the Purkinje network, during phase 0 of the action potential, thereby decreasing depolarization, automaticity and excitability.
Lidocaine Hydrochloride Synonyms
Lidocaine Hydrochloride, 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide Monohydrochloride, LIDOCAINE HYDROCHLORIDE, Xylocaine, Xylocitin, Xylotox
Terms in Lidocaine Hydrochloride category
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