Lopinavir
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Protease Inhibitor -> Lopinavir
Lopinavir Definition
A protease inhibitor used against human immunodeficiency virus (HIV). Lopinavir competitively inhibits the HIV-1 protease, an enzyme that mediates the cleavage of Gag, Gag-Pol and Nef precursor polypeptides into their mature proteins, including protease, reverse transcriptase, and integrase. Inhibition of HIV-1 protease prevents cleavage of the viral polyprotein precursor and results in the release of immature, noninfectious virions.
Lopinavir Synonyms
Lopinavir, ABT-378/r, LOPINAVIR
Terms in Lopinavir category
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