M-Phase Promoting Factor
Cancer Terms ->
Gene Product ->
Protein or Riboprotein Complex -> M-Phase Promoting Factor
M-Phase Promoting Factor Definition
M Phase-Promoting Factor is a protein kinase complex that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2.
M-Phase Promoting Factor Synonyms
M-Phase Promoting Factor, MPF, Mitosis-Promoting Factor
Terms in M-Phase Promoting Factor category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.