Cancer Terms

MERTK wt Allele

Cancer Terms -> Gene -> Ligand Binding Protein Gene -> Receptor Gene -> Receptor Tyrosine Kinase Gene -> MERTK Gene -> MERTK wt Allele

MERTK wt Allele Definition

Human MERTK wild-type allele is located in the vicinity of 2q14.1 and is approximately 131 kb in length. This allele, which encodes proto-oncogene tyrosine-protein kinase MER protein, plays a role in tissue homeostasis and receptor signaling. Mutations in the gene have been associated with disruption of the retinal pigment epithelium phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa.

MERTK wt Allele Synonyms

MERTK wt Allele, C-MER Proto-Oncogene Tyrosine Kinase wt Allele, MER, MERK, MERTK, c-mer

Terms in MERTK wt Allele category



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