MPL wt Allele

Cancer Terms -> Gene -> Ligand Binding Protein Gene -> Receptor Gene -> Cytokine Receptor Gene -> MPL Gene -> MPL wt Allele

MPL wt Allele Definition

Human MPL wild-type allele is located in the vicinity of 1p34.2 and is approximately 46 kb in length. This allele, which encodes thrombopoietin receptor protein, plays a role in megakaryocytopoiesis, hematopoesis and platelet formation. Defects in the gene cause congenital amegakaryocytic thrombocytopenia.

MPL wt Allele Synonyms

MPL wt Allele, C-MPL, CD110, MPLV, Myeloproliferative Leukemia Virus Oncogene wt Allele, TPOR, TPOR Gene, Thrombopoietin Receptor Gene

Terms in MPL wt Allele category

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