Memantine Hydrochloride
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Memantine Hydrochloride Definition
The hydrochloride salt of memantine, a low-affinity, voltage-dependent, noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. Memantine binds to and inhibits cation channels of glutamanergic NMDA receptors located in the central nervous system (CNS), preventing the prolonged influx of calcium ions and the associated neuronal excitotoxicity, and thereby potentially enhancing cognitive function. Memantine is also a 5-hydroxytryptamine type 3 (5HT3) receptor and nicotinic receptor antagonist.
Memantine Hydrochloride Synonyms
Memantine Hydrochloride, 1-amino-3,5-dimethyladamantane Hydrochloride, Ebixia, MEMANTINE HYDROCHLORIDE, Namenda
Terms in Memantine Hydrochloride category
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