Monoclonal Antibody Ch14 18
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Monoclonal Antibody Ch14 18 Definition
A chimeric mouse/human monoclonal antibody with potential antineoplastic activity. Monoclonal antibody Ch14.18 binds to the ganglioside GD2 and induces antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity against GD2-expressing tumor cells. GD2 is overexpressed in malignant melanoma, neuroblastoma, osteosarcoma, and small cell carcinoma of the lung. (NCI04)
Monoclonal Antibody Ch14 18 Synonyms
Monoclonal Antibody Ch14.18, Ch14.18, Ch14.18 Monoclonal Antibody, MoAb Ch14.18
Terms in Monoclonal Antibody Ch14 18 category
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