Monoclonal Antibody Lym-1
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Monoclonal Antibody Lym-1 Definition
A murine IgG2a monoclonal antibody directed against the HLA-Dr10 protein, a cell surface marker present on over eighty percent of lymphoma cells. When conjugated with a radioactive isotope, Lym-1 monoclonal antibody selectively transports the cytotoxic radioisotope to HLA-Dr10-expressing tumor cells, thereby sparing healthy B-cells and normal tissues. This agent also mediates antibody-dependent cytotoxicity thereby promoting Raji B-lymphoid cell lysis by human neutrophils. (NCI04)
Monoclonal Antibody Lym-1 Synonyms
Monoclonal Antibody Lym-1, IgG2a murine monoclonal antibody Lym-1, Lym-1, MoAb Lym-1, Monoclonal Antibody Lym-1, IgG2a Murine
Terms in Monoclonal Antibody Lym-1 category
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