Monoclonal Antibody RAV12
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Monoclonal Antibody RAV12 Definition
A chimeric monoclonal antibody directed against a primate-restricted N-linked carbohydrate epitope (glycotope) expressed on various human carcinomas with potential antineoplastic activity. Following binding, monoclonal antibody RAV12 disrupts sodium channels of tumor cells expressing this glycotope, resulting in cell and organelle swelling, loss of membrane integrity, and cell death. (NCI05)
Monoclonal Antibody RAV12 Synonyms
Monoclonal Antibody RAV12, anti-RAAG12 MOAB
Terms in Monoclonal Antibody RAV12 category
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