Multitargeted Receptor Tyrosine Kinase Inhibitor BAY 73-4506
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Multitargeted Receptor Tyrosine Kinase Inhibitor BAY 73-4506 Definition
An orally bioavailable small molecule with potential antiangiogenic and antineoplastic activities. Multikinase inhibitor BAY 73-4506 binds to and inhibits vascular endothelial growth factor receptors (VEGFRs) 2 and 3, and Ret, Kit, PDGFR and Raf kinases, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation. VEGFRs are receptor tyrosine kinases that play important roles in tumor angiogenesis; the receptor tyrosine kinases RET, KIT, and PDGFR, and the serine/threonine-specific Raf kinase are involved in tumor cell signaling.
Multitargeted Receptor Tyrosine Kinase Inhibitor BAY 73-4506 Synonyms
Multikinase Inhibitor BAY 73-4506, BAY 73-4506
Terms in Multitargeted Receptor Tyrosine Kinase Inhibitor BAY 73-4506 category
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