NOS2A wt Allele
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NOS2A wt Allele Definition
Human NOS2A wild-type allele is located within 17q11.2-q12 and is approximately 44 kb in length. This allele, which encodes nitric oxide synthase, inducible protein, plays a role in the biosynthesis of nitric oxide from L-arginine and molecular oxygen. NOS2A gene expression is up-regulated in liver cirrhosis and contributes to the progression of this disease state. The NOS2A gene is also involved in susceptibility to essential hypertension.
NOS2A wt Allele Synonyms
NOS2A wt Allele, NOS2, Nitric Oxide Synthase 2A (Inducible, Hepatocytes) wt Allele
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