Cancer Terms

NOVA Family Gene

Cancer Terms -> Gene -> Ligand Binding Protein Gene -> NOVA Family Gene

NOVA Family Gene Definition

Expressed in brain (neurons or astrocytes), NOVA Family Genes encode NOVA Family nuclear proteins (NOVA1, NOVA2), autoantigens in POMA recognized by IgG ANNA-2 that contain 3 KH domains and may regulate RNA splicing in neurons and astrocytes. NOVA proteins form structural complexes with other proteins. Found as one or multiple copies of a conserved 70-aa motif in diverse nucleic acid binding, and other, proteins, the KH domain binds RNA; each motif appears necessary for binding. (NCI)

NOVA Family Gene Synonyms

NOVA Family Gene

Terms in NOVA Family Gene category

NOVA1 Gene
NOVA2 Gene

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