NTRK1 wt Allele

Cancer Terms -> Gene -> Ligand Binding Protein Gene -> Receptor Gene -> Receptor Tyrosine Kinase Gene -> NTRK1 Gene -> NTRK1 wt Allele

NTRK1 wt Allele Definition

Human NTRK1 wild-type allele is located within 1q21-q22 and is approximately 21 kb in length. This allele, which encodes high affinity nerve growth factor receptor protein, is involved in cellular differentiation, signal transduction and may play a role in specifying sensory neuron subtypes. Defects in the gene have been associated with neoroblastomas and thyroid tumors. Further, mutations in the gene are associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and several other cancers.

NTRK1 wt Allele Synonyms

NTRK1 wt Allele, MTC, NTRK1, Neurotrophic Tyrosine Kinase, Receptor, Type 1 wt Allele, TRK, TRKA

NTRK1 wt Allele

NTRK1 wt Allele Definition

NTRK1 wt Allele Synonyms

Terms in NTRK1 wt Allele category