Netrin-1 Protein
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Netrin-1 Protein Definition
Widely expressed in adult tissues (highest in heart, small intestine, colon, liver, and prostate) by human NTN1 Gene (Laminin Family), 604-aa 68-kDa (precursor) Netrin 1 contains an N-terminal laminin domain, 3 laminin EGF-like domains, and an NTR domain. NTN1 binds to DCC and is thought to be involved in CNS and peripheral motor axon guidance and cell migration during development. Defects in NTN1 are associated with some neuroblastomas. (NCI)
Netrin-1 Protein Synonyms
Netrin 1, NTN1, NTN1L, Netrin 1 Homolog
Terms in Netrin-1 Protein category
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