ORC Subunit Gene

Cancer Terms -> Gene -> Replication Initiation Gene -> ORC Subunit Gene

ORC Subunit Gene Definition

DNA replication is initiated by the Origin Recognition Complex (ORC). ORC is composed of six protein subunits and binds to the ARS Consensus Sequence (ACS) of Origins of Replication in an ATP-dependent manner. While ORC remains bound to origins throughout the cell cycle, the binding of ORC and other factors modulates local chromatin structure to facilitate replication initiation. All 6 genes encoding ORC (ORC1 through ORC6) may be required for initiation of DNA replication and are essential for viability.

ORC Subunit Gene Synonyms

ORC Subunit Gene

Terms in ORC Subunit Gene category

ORC1L Gene
ORC2L Gene
ORC3L Gene
ORC4L Gene
ORC5L Gene
ORC6L Gene