PARP-1 Inhibitor AG014699
Cancer Terms ->
Drugs and Chemicals ->
Pharmacologic Substance ->
Enzyme Inhibitor ->
Poly ADP-Ribose Polymerase Inhibitor -> PARP-1 Inhibitor AG014699
PARP-1 Inhibitor AG014699 Definition
A tricyclic indole poly(ADP-Ribose) polymerase (PARP) inhibitor with potential antineoplastic activity. PARP-1 inhibitor AG014699 blocks base excision repair mediated by PARP 1 on single strand breaks and may be particularly efficacious in inducing apoptosis in breast cancer associated gene-1 and -2 (BRCA1/2) deficient tumor cells.
PARP-1 Inhibitor AG014699 Synonyms
PARP1 Inhibitor AG014699, AG014699
Terms in PARP-1 Inhibitor AG014699 category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.