PDGFRB wt Allele

Cancer Terms -> Gene -> Ligand Binding Protein Gene -> Receptor Gene -> Receptor Tyrosine Kinase Gene -> PDGFRB Gene -> PDGFRB wt Allele

PDGFRB wt Allele Definition

Human PDGFRB wild-type allele is located within 5q31-q32 and is approximately 42 kb in length. This allele, which encodes beta platelet-derived growth factor receptor protein, is involved in mitogenesis for cells of mesenchymal origin. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

PDGFRB wt Allele Synonyms

PDGFRB wt Allele, CD140B, JTK12, PDGF-R-Beta, PDGFR, PDGFR Beta, PDGFR1, PDGFRB, Platelet-Derived Growth Factor Receptor, Beta Polypeptide wt Allele

Terms in PDGFRB wt Allele category

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