Cancer Terms

PTTG1 wt Allele

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PTTG1 wt Allele Definition

Human PTTG1 wild-type allele is located in the vicinity of 5q35.1 and is approximately 7 kb in length. This allele, which encodes securing protein, plays a role in chromatid separation. Thus, this allele affects cycle regulation, proliferation and cellular transformation; as variant alleles are highly expressed in many tumors.

PTTG1 wt Allele Synonyms

PTTG1 wt Allele, PTTG, Pituitary Tumor Transforming Gene, Pituitary Tumor-Transforming 1 wt Allele, TUTR1, hPTTG

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