Protein Truncation Abnormality
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Protein Sequence Abnormality -> Protein Truncation Abnormality
Protein Truncation Abnormality Definition
Translation of a truncated form of a wild-type protein that originates from a mutation or mutations in the coding sequence of a gene. Genetic alterations that yield truncated protein products include frameshift mutations, nonsense mutations or splice site mutations. The activity of a truncated protein is usually reduced or abolished in comparison to the activity of the wild-type protein.
Protein Truncation Abnormality Synonyms
Protein Truncation Abnormality, Protein Truncation, Truncation
Terms in Protein Truncation Abnormality category
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