RAL Guanine Nucleotide Dissociation Stimulator
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RAL Guanine Nucleotide Dissociation Stimulator Definition
Encoded by human RALGDS Gene, 914-aa 101-kDa RAL Guanine Nucleotide Dissociation Stimulator is a guanine nucleotide exchange factor containing an N-terminal RAS-GEF domain and a noncatalytic C-terminal RAS-associating domain. RALGDS interaction as an effector molecule with RAS-like molecules is specific and dependent on RAS activation by GTP. RALGDS stimulates dissociation of GDP from RAS-related RALA and RALB GTPases, allowing GTP binding and GTPase activation. (NCI)
RAL Guanine Nucleotide Dissociation Stimulator Synonyms
RAL Guanine Nucleotide Dissociation Stimulator, RALGDS, RALGEF, RGF
Terms in RAL Guanine Nucleotide Dissociation Stimulator category
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