RAS-Related Protein-RAP1A
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RAS-Related Protein-RAP1A Definition
Encoded by human RAP1A Gene (RAS GTPase Family), 184-aa 21-kDa (precursor) membrane-bound RAS-Related Protein RAP1A is activated by guanine nucleotide-exchange factors EPAC and EPAC2, in a cAMP-dependent manner, and by GFR. Interacting with RAS GAPs and RAF in a competitive manner, RAP1A counteracts RAS mitogenic function. (NCI)
RAS-Related Protein-RAP1A Synonyms
RAS-Related Protein RAP1A, C21KG, G-22K, GTP-Binding Protein SMG-P21A, KREV-1 Protein, RAP1A, RAP1A Member of RAS Oncogene Family, SMGP21
Terms in RAS-Related Protein-RAP1A category
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