Cancer Terms

RC-1291 Ghrelin Mimetic

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Agent Affecting Musculoskeletal System -> Anticachexia Agent -> RC-1291 Ghrelin Mimetic

RC-1291 Ghrelin Mimetic Definition

A synthetic, orally bioavailable, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. RC-1291 ghrelin mimetic binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of ghrelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite.

RC-1291 Ghrelin Mimetic Synonyms

Anamorelin, ANAMORELIN, RC-129

Terms in RC-1291 Ghrelin Mimetic category



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