Ranpirnase
Cancer Terms ->
Drugs and Chemicals ->
Pharmacologic Substance ->
Protein Synthesis Inhibitor -> Ranpirnase
Ranpirnase Definition
A natural homologue of ribonuclease A isolated from the eggs of the frog Rana pipiens. Ranpirnase primarily degrades cellular transfer RNA with a substrate specificity for uridine-guanidine base-pair sequences, resulting in inhibition of protein synthesis and cytotoxicity. This agent also activates caspase-9 in mitochondria, resulting in tumor cell apoptosis. (NCI04)
Ranpirnase Synonyms
Ranpirnase, Onconase, P-30, P-30 Protein, P-30 protein, P30, P30 Protein
Terms in Ranpirnase category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.