Recombinant Human Hyaluronidase
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Recombinant Human Hyaluronidase Definition
A human recombinant form of the naturally occurring human enzyme hyaluronidase with potential chemoadjuvant activity. Upon local administration, recombinant human hyaluronidase hydrolyzes hyaluronic acid, a glucosaminoglycan responsible for the viscosity of the interstitial barrier. The digestion of hyaluronic acid lowers the viscosity in the interstitial space, thereby increasing permeability and facilitating local penetration of chemotherapeutic agents into cancer cells.
Recombinant Human Hyaluronidase Synonyms
Recombinant Human Hyaluronidase, Chemophase, HYALURONIDASE RECOMBINANT HUMAN, Hyaluronidase Recombinant Human, Hylenex, rHuPH20
Terms in Recombinant Human Hyaluronidase category
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