Recombinant Tissue Plasminogen Activator
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Recombinant Tissue Plasminogen Activator Definition
A recombinant therapeutic agent which is chemically identical to or similar to endogenous tissue plasminogen activator (tPA). tPA is a serine protease which converts plasminogen to plasmin, a fibrinolytic enzyme. Upon administration, recombinant tPA increases plasmin enzymatic activity, resulting in hyperfibrinolysis and potential dissolution of a thrombus or embolism. (NCI05)
Recombinant Tissue Plasminogen Activator Synonyms
Alteplase, ALTEPLASE, Activase, Plasminogen Activator (Human Tissue-Type Protein Moiety), Recombinant Tissue Plasminogen Activator, rt-PA
Terms in Recombinant Tissue Plasminogen Activator category
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