SDZ 280-446
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Multidrug Resistance Modulator -> SDZ 280-446
SDZ 280-446 Definition
A novel semi-synthetic derivative of cyclosporin and a cyclodepsipeptide with chemo-sensitizing activity. SDZ 280-446 is one of the drug resistance-modifying agents that inhibit P-glycoprotein, the multidrug resistance efflux pump, thereby restoring the retention and activities of some drugs in drug-resistant tumor cells.
SDZ 280-446 Synonyms
SDZ 280-446
Terms in SDZ 280-446 category
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