Cancer Terms

ST14 wt Allele

Cancer Terms -> Gene -> Enzyme Gene -> Hydrolase Gene -> Protease Gene -> ST14 Gene -> ST14 wt Allele

ST14 wt Allele Definition

Human ST14 wild-type allele is located within 11q24-q25 and is approximately 51 kb in length. This allele, which encodes suppressor of tumorigenicity 14 protein, is involved in the cleavage/activation of other proteases and latent growth factors. Decreased expression of the ST14 gene is associated with tumor metastasis.

ST14 wt Allele Synonyms

ST14 wt Allele, HAI, MT-SP1, MTSP-1, MTSP1, PRSS14, SNC19, Suppression of Tumorigenicity 14 (Colon Carcinoma, Matriptase, Epithin) wt Allele, TADG-15, TADG15

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