Sp1 Activation Cofactor Gene

Cancer Terms -> Gene -> Regulatory Gene -> Transcription Coregulator Gene -> Transcription Coactivator Gene -> Sp1 Activation Cofactor Gene

Sp1 Activation Cofactor Gene Definition

Sp1 Activation Cofactor Genes encode (at least 9) protein subunits of the CRSP (Cofactor Required for SP1 activation) complex, which, along with TFIID, is required for efficient activation of gene transcription by SP1, a transcription factor that recognizes enhancer sites in target DNA. Many CRSP complex proteins are also components of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins that interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. (NCI)

Sp1 Activation Cofactor Gene Synonyms

Terms in Sp1 Activation Cofactor Gene category

CRSP2 Gene
CRSP3 Gene
CRSP4 Gene
CRSP6 Gene
CRSP7 Gene
CRSP8 Gene
CRSP9 Gene