Sulfasalazine
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Sulfasalazine Definition
A synthetic salicylic acid derivative with affinity for connective tissues containing elastin and formulated as a prodrug, antiinflammatory Sulfasalazine acts locally in the intestine through its active metabolites, sulfamide 5-aminosalicylic acid and salicylic acid, by a mechanism that is not clear. It appears inhibit cyclooxygenase and prostaglandin production and is used in the management of inflammatory bowel diseases. (NCI04)
Sulfasalazine Synonyms
Sulfasalazine, 2-Hydroxy-5-[[4-[(2-pyridinylamino)sulfonyl]phenyl]azo]benzoic Acid, Azulfidine, SULFASALAZINE, Salazosulfapyridine, Sulphasalazine
Terms in Sulfasalazine category
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