Cancer Terms

Sumoylation Regulation of Transcriptional Repression Pathway

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Sumoylation Regulation of Transcriptional Repression Pathway Definition

Current data indicates that nuclear pore complex (NPC) RanBP2 (SUMO E3 ligase) protein sumoylates Mdm2 and HDAC proteins during nuclear translocation. A sumoylation-deficient HDAC showed reduced deacetylation activity and suggests that sumoylation may be an important regulatory mechanism for the control of transcriptional repression. (BioCarta)

Sumoylation Regulation of Transcriptional Repression Pathway Synonyms

Sumoylation Regulation of Transcriptional Repression Pathway, Sumoylation by RanBP2 Regulates Transcriptional Repression

Terms in Sumoylation Regulation of Transcriptional Repression Pathway category



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